Federal partners work closely with each other as well as with state and local agencies, private companies, and consumers to address food safety from farm to table. The Centers for Disease Control and Prevention (CDC) and state public health agencies are responsible for monitoring, identifying, and investigating foodborne illness and outbreaks. CDC coordinates closely with FDA and USDA as the U.S. regulatory authorities for food products. The U.S. capacity to detect and respond to foodborne outbreaks, including those that result in a public health emergency, has improved dramatically in the past two decades. Since 1996, CDC has used DNA "fingerprinting" of bacteria (including whole genome sequencing) to enhance outbreak detection and define the scope and scale of outbreaks beyond traditional methods. That system, PulseNet consists of over 80 federal, state, and local laboratories in the United States. CDC works closely with State and local health departments who have the primary statutory authority and responsibility for disease surveillance. Most foodborne outbreaks are local events in just one city or county; local public health officials investigate those outbreaks. State health departments investigate outbreaks that spread across several cities or counties. Those health departments often work with their departments of agriculture and with federal food safety agencies as needed. In partnership with FDA and FSIS, CDC typically leads investigations of multistate outbreaks – those that affect many states at once. However, the Federal Bureau of Investigation (FBI) is the lead federal agency for law enforcement investigations of any potentially intentional biological or chemical threat or incident, such as, but not limited to, food adulteration.